The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

<p>Abstract</p> <p>Background</p> <p>The conserved CD4 binding site (CD4bs) on HIV-1 gp120 is a major target for vaccines. It is a priority to determine sites and structures within the CD4bs that are important for inclusion in vaccines. We studied a gp120 pocket penetra...

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Bibliographic Details

Published in:	Retrovirology
Main Authors:	Dueñas-Decamp Maria J, O'Connell Olivia J, Corti Davide, Zolla-Pazner Susan, Clapham Paul R
Format:	Article
Language:	English
Published:	BMC 2012-01-01
Subjects:	HIV envelope gp120 CD4 binding site neutralization
Online Access:	http://www.retrovirology.com/content/9/1/9