Characterization of a Clinically and Biologically Defined Subgroup of Patients with Autism Spectrum Disorder and Identification of a Tailored Combination Treatment

Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders (NDDs) with a high unmet medical need. The diagnosis of ASD is currently based on behavior criteria, which overlooks the diversity of genetic, neurophysiological, and clinical manifestations. Failure to acknowled...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Laura Pérez-Cano, Luigi Boccuto, Francesco Sirci, Jose Manuel Hidalgo, Samuel Valentini, Mattia Bosio, Xavier Liogier D’Ardhuy, Cindy Skinner, Lauren Cascio, Sujata Srikanth, Kelly Jones, Caroline B. Buchanan, Steven A. Skinner, Baltazar Gomez-Mancilla, Jean-Marc Hyvelin, Emre Guney, Lynn Durham
Format:	Article
Language:	English
Published:	MDPI AG 2024-04-01
Subjects:	precision medicine ASD Phenotype 1 metabolic and transcriptomic alterations NF-κB NRF2 Warburg effect
Online Access:	https://www.mdpi.com/2227-9059/12/5/991