Novel microRNAs modulating ecto-5′-nucleotidase expression

IntroductionThe expression of immune checkpoint molecules (ICMs) by cancer cells is known to counteract tumor-reactive immune responses, thereby promoting tumor immune escape. For example, upregulated expression of ecto-5′-nucleotidase (NT5E), also designated as CD73, increases extracellular levels...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Theresa Kordaß, Tsu-Yang Chao, Wolfram Osen, Stefan B. Eichmüller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1199374/full