Molecular crosstalk in SP7-mediated osteogenesis: Regulatory mechanisms and therapeutic potential

SP7, also known as Osterix, is a zinc finger-containing transcription factor, plays a crucial role in osteoblast differentiation and bone formation. This review examines the molecular mechanisms underlying SP7's regulatory functions, highlighting its interactions with key signaling pathways suc...

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Bibliographic Details

Published in:	Osteoporosis and Sarcopenia
Main Authors:	Jun Lang, Vivek Kumar Morya, Mi-Kyung Kwak, Sin-Hye Park, Kyu-Cheol Noh
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	SP7 SOST BMP HIF-1α Osteogenesis Osteoporosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405525525000251