Optimisation of a Microfluidic Method for the Delivery of a Small Peptide

Peptides hold promise as therapeutics, as they have high bioactivity and specificity, good aqueous solubility, and low toxicity. However, they typically suffer from short circulation half-lives in the body. To address this issue, here, we have developed a method for encapsulation of an innate-immune...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Felicity Y. Han, Weizhi Xu, Vinod Kumar, Cedric S. Cui, Xaria Li, Xingyu Jiang, Trent M. Woodruff, Andrew K. Whittaker, Maree T. Smith
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Subjects:	drug delivery system nanoparticles poly (lactic-<i>co</i>-glycolic acid) (PLGA) microfluidic pharmacokinetics (PK) and biodistribution
Online Access:	https://www.mdpi.com/1999-4923/13/9/1505