DG-Affinity: predicting antigen–antibody affinity with language models from sequences

Abstract Background Antibody-mediated immune responses play a crucial role in the immune defense of human body. The evolution of bioengineering has led the progress of antibody-derived drugs, showing promising efficacy in cancer and autoimmune disease therapy. A critical step of this development pro...

Full description

Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Ye Yuan, Qushuo Chen, Jun Mao, Guipeng Li, Xiaoyong Pan
Format:	Article
Language:	English
Published:	BMC 2023-11-01
Subjects:	Affinity Deep learning Sequence embedding Antibody–antigen interaction
Online Access:	https://doi.org/10.1186/s12859-023-05562-z