Celastrol Alleviates Airway Hyperresponsiveness and Inhibits Th17 Responses in Obese Asthmatic Mice

Severe airway hyperresponsiveness (AHR) is a clinical feature of asthma, which has been associated with obesity and has shown a poor response to standard asthma treatments such as glucocorticoids. Numerous studies have shown that Interleukin (IL)-17 producing CD4+T cells (Th17 cells), which could be...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Pharmacology
المؤلفون الرئيسيون: Zeyu Zeng, Xixi Lin, Rongying Zheng, Hui Zhang, Weixi Zhang
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2018-01-01
الموضوعات:
celastrol
obese
asthma
airway hyperresponsiveness
T help cell 17
الوصول للمادة أونلاين:http://journal.frontiersin.org/article/10.3389/fphar.2018.00049/full

الانترنت

http://journal.frontiersin.org/article/10.3389/fphar.2018.00049/full

مواد مشابهة