FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

Abstract FBXW7 is a member of the F-box protein family, which functions as the substrate recognition component of the SCF E3 ubiquitin ligase. FBXW7 is a main tumor suppressor due to its ability to control proteasome-mediated degradation of several oncoproteins such as c-Jun, c-Myc, Cyclin E1, mTOR,...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Rafael Jiménez-Izquierdo, Rosario Morrugares, Lucía Suanes-Cobos, Alejandro Correa-Sáez, Martín Garrido-Rodríguez, Laura Cerero-Tejero, Omar M. Khan, Susana de la Luna, Rocío Sancho, Marco A. Calzado
Format:	Article
Language:	English
Published:	Nature Publishing Group 2023-03-01
Online Access:	https://doi.org/10.1038/s41419-023-05724-0