Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic <i>Pseudogymnoascus</i> sp. HDN17-933

Chemical investigation of the psychrophilic fungus <i>Pseudogymnoascus</i> sp. HDN17-933 derived from Antarctica led to the discovery of six new tetrapeptides psegymamides A–F (<b>1</b>–<b>6</b>), whose planar structures were elucidated by extensive NMR and MS spe...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Xuewen Hou, Changlong Li, Runfang Zhang, Yinping Li, Huadong Li, Yundong Zhang, Han-Shen Tae, Rilei Yu, Qian Che, Tianjiao Zhu, Dehai Li, Guojian Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	psychrophilic fungus tetrapeptides tetrahydropyridoindoles unit solid-phase synthesis nicotinic acetylcholine receptors molecular docking
Online Access:	https://www.mdpi.com/1660-3397/20/10/593