Anti-gastric cancer activity of 1,2,3-triazolo[4,5-d]pyrimidine hybrids (1,2,3-TPH): QSAR and molecular docking approaches

Gastric cancer as a dreaded disease which occurs in the digestive system of human being remain a threat to the medical world. Bioactivity of series of designed and synthesized molecular compounds containing triazole and pyrimidine moieties were subjected to quantum chemical calculations using B3LYP/...

Full description

Bibliographic Details

Published in:	Heliyon
Main Authors:	Oyebamiji Abel Kolawole, Fadare Olatomide A, Semire Banjo
Format:	Article
Language:	English
Published:	Elsevier 2020-03-01
Subjects:	Theoretical chemistry Pharmaceutical chemistry 1, 2, 3-triazolo[4, 5-d]pyrimidine hybrids DFT QSAR Molecular docking
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844020304060