Inhibition of serum and glucocorticoid regulated kinase-1 as novel therapy for cardiac arrhythmia disorders

Abstract Alterations in sodium flux (INa) play an important role in the pathogenesis of cardiac arrhythmias and may also contribute to the development of cardiomyopathies. We have recently demonstrated a critical role for the regulation of the voltage-gated sodium channel NaV1.5 in the heart by the...

詳細記述

書誌詳細
出版年:Scientific Reports
主要な著者: Vassilios J. Bezzerides, Aifeng Zhang, Ling Xiao, Bridget Simonson, Santosh A. Khedkar, Shiro Baba, Filomena Ottaviano, Stacey Lynch, Katherine Hessler, Alan C. Rigby, David Milan, Saumya Das, Anthony Rosenzweig
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2017-03-01
オンライン・アクセス:https://doi.org/10.1038/s41598-017-00413-3