Intercellular transmission of pathogenic proteins in ALS: Exploring the pathogenic wave

ABSTRACT: In patients with amyotrophic lateral sclerosis (ALS), disease symptoms and pathology typically spread in a predictable spatiotemporal pattern beginning at a focal site of onset and progressing along defined neuroanatomical tracts. Like other neurodegenerative diseases, ALS is characterized...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	F.J. Arnold, A.D. Nguyen, R.S. Bedlack, C.L. Bennett, A.R. La Spada
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Subjects:	ALS Cell-to-cell propagation Oligomerization Extracellular-vesicles Endocytosis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996123002334