Pre-transplant CD69+ extracellular vesicles are negatively correlated with active ATLG serum levels and associate with the onset of GVHD in allogeneic HSCT patients

Graft versus host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplantation (HSCT). Rabbit anti-T lymphocyte globulin (ATLG) in addition to calcineurin inhibitors and antimetabolites is a suitable strategy to prevent GVHD in several transplant settings. Randomized...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Gianluca Storci, Francesco Barbato, Francesca Ricci, Pier Luigi Tazzari, Serena De Matteis, Enrica Tomassini, Michele Dicataldo, Noemi Laprovitera, Mario Arpinati, Margherita Ursi, Enrico Maffini, Elena Campanini, Elisa Dan, Silvia Manfroi, Spartaco Santi, Manuela Ferracin, Massimiliano Bonafe, Francesca Bonifazi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	anti-T lymphocyte globulin graft versus host disease extracellular vesicles CD69 CD103
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1058739/full