Changes in the excitability of the medial parabrachial nucleus neurons during the chronic phase of pilocarpine-induced epilepsy in mice

IntroductionEpilepsy is a common and serious brain disorder that often co-occurs with sleep disturbances. Sodium valproate, a conventional antiepileptic drug, alleviates sleep disorders in patients with epilepsy; however, the exact underlying mechanism remains unclear. The medial parabrachial nucleu...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Jinyu Xiao, Yinghui Gu, Chunhua Quan, Shulei Li, Jianmin Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-03-01
Subjects:	medial parabrachial nucleus neurons pilocarpine epilepsy glial fibrillary acidic protein neuronal activity FosB/ΔFosB
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1474254/full