Transcriptome analysis combined with single-cell analysis identified that APOC1 influences cholesterol transport by macrophages in ccRCC

Abstract Renal cell carcinoma (RCC) is one of the most prevalent categories of cancer worldwide, accounting for approximately 2% of cancer diagnoses and cancer deaths worldwide. various immunotherapeutic strategies have emerged as key approaches to managing advanced RCC. Bioinformatics methodologies...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Fengran Guo, Ziyang Ma, Hu Wang, Zhenwei Han
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Subjects:	Single-cell RNA sequencing ccRCC Apoptosis APOC1 Immunity
Online Access:	https://doi.org/10.1038/s41598-025-18392-1