Posthemorrhagic hydrocephalus associates with elevated inflammation and CSF hypersecretion via activation of choroidal transporters

Abstract Introduction Posthemorrhagic hydrocephalus (PHH) often develops following hemorrhagic events such as intraventricular hemorrhage (IVH) and subarachnoid hemorrhage (SAH). Treatment is limited to surgical diversion of the cerebrospinal fluid (CSF) since no efficient pharmacological therapies...

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Bibliographic Details

Published in:	Fluids and Barriers of the CNS
Main Authors:	Sara Diana Lolansen, Nina Rostgaard, Dagne Barbuskaite, Tenna Capion, Markus Harboe Olsen, Nicolas H. Norager, Frederik Vilhardt, Søren Norge Andreassen, Trine L. Toft-Bertelsen, Fenghui Ye, Marianne Juhler, Richard F. Keep, Nanna MacAulay
Format:	Article
Language:	English
Published:	BMC 2022-08-01
Subjects:	Intraventricular hemorrhage Subarachnoid hemorrhage Posthemorrhagic hydrocephalus Cerebrospinal fluid Immune response Biomarkers
Online Access:	https://doi.org/10.1186/s12987-022-00360-w