Decoding the pathogenesis of Diamond–Blackfan anemia using single-cell RNA-seq

Abstract Ribosomal protein dysfunction causes diverse human diseases, including Diamond–Blackfan anemia (DBA). Despite the universal need for ribosomes in all cell types, the mechanisms underlying ribosomopathies, which are characterized by tissue-specific defects, are still poorly understood. In th...

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Bibliographic Details

Published in:	Cell Discovery
Main Authors:	Bingrui Wang, Chenchen Wang, Yang Wan, Jie Gao, Yige Ma, Yingnan Zhang, Jingyuan Tong, Yingchi Zhang, Jinhua Liu, Lixian Chang, Changlu Xu, Biao Shen, Yumei Chen, Erlie Jiang, Ryo Kurita, Yukio Nakamura, Kim-Chew Lim, James Douglas Engel, Jiaxi Zhou, Tao Cheng, Xiaofan Zhu, Ping Zhu, Lihong Shi
Format:	Article
Language:	English
Published:	Nature Publishing Group 2022-05-01
Online Access:	https://doi.org/10.1038/s41421-022-00389-z