Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia

Abstract Background Oxidative stress and damage are associated with a number of ageing phenotypes, including age‐related loss of muscle mass and reduced contractile function (sarcopenia). Our group and others have reported loss of neuromuscular junction (NMJ) integrity and increased denervation as i...

Full description

Bibliographic Details

Published in:	Journal of Cachexia, Sarcopenia and Muscle
Main Authors:	Hongyang Xu, Rojina Ranjit, Arlan Richardson, Holly Van Remmen
Format:	Article
Language:	English
Published:	Wiley 2021-12-01
Subjects:	Skeletal muscle Mitochondria Neuromuscular junction ROS Oxidative stress Catalase
Online Access:	https://doi.org/10.1002/jcsm.12768