Subcutaneous Immunization with Unaltered Axenic Malaria Parasite Liver Stages Induces Sterile Protection against Infectious Sporozoite Challenge

Host cell-free, axenic development of liver stages (LS) of the malaria parasite has been demonstrated. Here we explored axenic liver stages as a novel live whole parasite malaria vaccine platform, which is unaltered and not prone to human-error, compared to the immunization with live-attenuated spor...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Vaccines
المؤلفون الرئيسيون:	Mohd Kamil, Gozde Deveci, Umit Y. Kina, Stefan H. I. Kappe, Ahmed S. I. Aly
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	MDPI AG 2022-11-01
الموضوعات:	malaria vaccine axenic liver stage subcutaneous immunization <i>Plasmodium yoelii</i>
الوصول للمادة أونلاين:	https://www.mdpi.com/2076-393X/10/11/1884