Pseudomonas aeruginosa quorum sensing and biofilm attenuation by a di-hydroxy derivative of piperlongumine (PL-18)

Bacterial communication, Quorum Sensing (QS), is a target against virulence and prevention of antibiotic-resistant infections. 16 derivatives of Piperlongumine (PL), an amide alkaloid from Piper longum L., were screened for QS inhibition. PL-18 had the best QSI activity. PL-18 inhibited the lasR-las...

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發表在:	Biofilm
Main Authors:	Yael Schlichter Kadosh, Subramani Muthuraman, Khairun Nisaa, Anat Ben-Zvi, Danit Lisa Karsagi Byron, Marilou Shagan, Alexander Brandis, Tevie Mehlman, Jacob Gopas, Rajendran Saravana Kumar, Ariel Kushmaro
格式:	Article
語言:	英语
出版:	Elsevier 2024-12-01
主題:	Piperlongumine Piper longum Amide alkaloid Pseudomonas aeruginosa Quorum sensing Bacterial biofilm
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2590207524000406