Stability of APOBEC3F in the Presence of the APOBEC3 Antagonist HIV-1 Vif Increases at the Expense of Co-Expressed APOBEC3H Haplotype I

The seven human APOBEC3 enzymes (APOBEC3A through H, excluding E) are host restriction factors. Most of the APOBEC3 enzymes can restrict HIV-1 replication with different efficiencies. The HIV-1 Vif protein combats APOBEC3-mediated restriction by inducing ubiquitination and degradation in the proteas...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Maria Yousefi, Arun Kumar Annan Sudarsan, Amit Gaba, Linda Chelico
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	restriction factor HIV-1 APOBEC3
Online Access:	https://www.mdpi.com/1999-4915/15/2/463