Biomarkers of cytokine release syndrome and neurotoxicity related to CAR-T cell therapy

Abstract Severe cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T cell (CAR-T) therapy can be life-threatening in some cases, and management of those toxicities is still a great challenge for physicians. Researchers hope to understand the pathophysiology of CRS...

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Bibliographic Details

Published in:	Biomarker Research
Main Authors:	Zhenguang Wang, Weidong Han
Format:	Article
Language:	English
Published:	BMC 2018-01-01
Subjects:	Chimeric antigen receptor CAR-T CRS Neurotoxicity Biomarker
Online Access:	http://link.springer.com/article/10.1186/s40364-018-0116-0