Diabetic Glycation of Human Serum Albumin Affects Its Immunogenicity

Advanced glycation end-products (AGEs) are products of a non-enzymatic reaction between amino acids and reducing sugars. Glycated human serum albumin (HSA) increases in diabetics as a consequence of elevated blood glucose levels and glycating metabolites like methylglyoxal (MGO). The impact of diffe...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Cresci-Anne C. C. Croes, Marialena Chrysanthou, Tamara Hoppenbrouwers, Harry Wichers, Jaap Keijer, Huub F. J. Savelkoul, Malgorzata Teodorowicz
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Subjects:
diabetes
AGEs
HSA
RAGE
macrophages
inflammation
Online Access:https://www.mdpi.com/2218-273X/14/12/1492

Internet

https://www.mdpi.com/2218-273X/14/12/1492

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