Impact of Difluoromethylornithine and AMXT 1501 on Gene Expression and Capsule Regulation in <i>Streptococcus pneumoniae</i>

<i>Streptococcus pneumoniae</i> (Spn), a Gram-positive bacterium, poses a significant threat to human health, causing mild respiratory infections to severe invasive conditions. Despite the availability of vaccines, challenges persist due to serotype replacement and antibiotic resistance,...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Moses B. Ayoola, Leslie A. Shack, Otto Phanstiel, Bindu Nanduri
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Subjects:	<i>Streptococcus pneumoniae</i> polyamine DFMO AMXT 1501 capsule
Online Access:	https://www.mdpi.com/2218-273X/14/2/178