Rewiring the bone marrow: Evolution and the transcriptional architecture of trained immunity

The epigenetic adaptation of innate immune cells to inflammatory stimuli, or trained immunity, represents an evolutionarily conserved feature of host defense. Recent advances have revealed that such adaptations can occur at the level of hematopoietic stem and progenitor cells, resulting in long-last...

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Bibliographic Details
Published in:eLife
Main Authors: Sarah J Sun, Raúl Aguirre-Gamboa, Luis B Barreiro
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-10-01
Subjects:
Online Access:https://elifesciences.org/articles/107551