Pre-Infection Innate Immunity Attenuates SARS-CoV-2 Infection and Viral Load in iPSC-Derived Alveolar Epithelial Type 2 Cells

A large portion of the heterogeneity in coronavirus disease 2019 (COVID-19) susceptibility and severity of illness (SOI) remains poorly understood. Recent evidence suggests that SARS-CoV-2 infection-associated damage to alveolar epithelial type 2 cells (AT2s) in the distal lung may directly contribu...

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Bibliographic Details
Published in:Cells
Main Authors: Satish Kumar, Jose Granados, Miriam Aceves, Juan Peralta, Ana C. Leandro, John Thomas, Sarah Williams-Blangero, Joanne E. Curran, John Blangero
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Subjects:
iPSCs
AT2s
COVID-19
in vitro modeling
innate immunity
Online Access:https://www.mdpi.com/2073-4409/13/5/369

Internet

https://www.mdpi.com/2073-4409/13/5/369

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