Fatal acute-on-chronic liver failure following camrelizumab for hepatocellular carcinoma with HBsAg seroclearance: a case report and literature review

In the last few years, immune checkpoint inhibitors (ICIs) have become major therapeutic agents for the treatment of advanced hepatocellular carcinoma (HCC). However, immunotherapy can activate hepatitis B virus (HBV), and immune clearance may lead to liver failure and even life-threatening conditio...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Fenghui Li, Tao Wang, Fei Tang, Jing Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Subjects:	immune checkpoint inhibitors (ICIs) immune-mediated liver injury caused by checkpoint inhibitors (ILICI) hepatitis B clearance of HBsAg liver failure
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2023.1231597/full