A novel role for the RNA-binding protein FXR1P in myoblasts cell-cycle progression by modulating p21/Cdkn1a/Cip1/Waf1 mRNA stability.

The Fragile X-Related 1 gene (FXR1) is a paralog of the Fragile X Mental Retardation 1 gene (FMR1), whose absence causes the Fragile X syndrome, the most common form of inherited intellectual disability. FXR1P plays an important role in normal muscle development, and its absence causes muscular abno...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Genetics
المؤلفون الرئيسيون: Laetitia Davidovic, Nelly Durand, Olfa Khalfallah, Ricardo Tabet, Pascal Barbry, Bernard Mari, Sabrina Sacconi, Hervé Moine, Barbara Bardoni
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Public Library of Science (PLoS) 2013-03-01
الوصول للمادة أونلاين:http://europepmc.org/articles/PMC3605292?pdf=render