Small molecule anion carriers facilitate lactate transport in model liposomes and cells

Summary: An excessive production of lactate by cancer cells fosters tumor growth and metastasis. Therefore, targeting lactate metabolism and transport offers a new therapeutic strategy against cancer, based on dependency of some cancer cells for lactate as energy fuel or as oncogenic signal. Herein...

Full description

Bibliographic Details

Published in:	iScience
Main Authors:	Daniel Alonso-Carrillo, Alain Arias-Betancur, Israel Carreira-Barral, Pere Fontova, Vanessa Soto-Cerrato, María García-Valverde, Ricardo Pérez-Tomás, Roberto Quesada
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	Natural sciences Biological sciences Biochemistry Molecular biology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223019752