Danos oxidativos e neurodegeneração: o quê aprendemos com animais transgênicos e nocautes?

Accumulated evidence indicates that oxidative stress plays a role in neurodegenerative diseases, such as Alzheimer, Parkinson and Amyotrophic Lateral Sclerosis. Here, we emphasize the results provided by the technology of genetically modified animals. Studies with transgenic and knockout mice have a...

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Bibliographic Details

Published in:	Química Nova
Main Authors:	Lívea Fujita Barbosa, Marisa H.G. de Medeiros, Ohara Augusto
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Química 2006-12-01
Subjects:	oxidative damage neurodegeneration transgenic knockout mice
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000600034&lng=en&tlng=en