Zinc oxide nanoparticles-induced testis damage at single-cell resolution: Depletion of spermatogonia reservoir and disorder of Sertoli cell homeostasis

The widespread application of zinc oxide nanoparticles (ZnO NPs) in our daily life has initiated an enhanced awareness of their biosafety concern. An incredible boom of evidence of organismal disorder has accumulated for ZnO NPs, yet there has been no relevant study at the single-cell level. Here, w...

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Bibliographic Details

Published in:	Environment International
Main Authors:	Tong Chen, Lin Zhang, Liangyu Yao, Jiaochen Luan, Xiang Zhou, Rong Cong, Xuejiang Guo, Chao Qin, Ninghong Song
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	Fatty acid accumulation scRNA-seq Sertoli cells Spermatogonia Testis damage ZnO NPs
Online Access:	http://www.sciencedirect.com/science/article/pii/S0160412023005652