Discovery of small molecules with anthelmintic potential in the Medicines for Malaria Venture’s COVID and Global Health Priority Boxes using an infrared-based assay for Caenorhabditis elegans motility

Abstract Background Parasitic nematodes are a public health problem globally, and an economic burden on animal and plant agricultural industries. With their ability to generate drug resistance, new anthelmintic compounds must be constantly sourced. Methods Using the free-living nematode, Caenorhabdi...

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Bibliographic Details

Published in:	BMC Research Notes
Main Authors:	Yujie Uli Sun, Lawrence J. Liu, Conor R. Caffrey
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Whole-organism screen Caenorhabditis elegans Anthelmintic Drug discovery Parasite Medicines for Malaria Venture
Online Access:	https://doi.org/10.1186/s13104-025-07485-9