Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways

Sivelestat sodium (SIV), a neutrophil elastase inhibitor, is mainly used for the clinical treatment of acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). However, studies investigating the effects of SIV treatment of ALI are limited. Therefore, this study investigated the potenti...

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發表在:	Biomolecules & Biomedicine
Main Authors:	Hong Zhang, Jun Zeng, Jiankang Li, Huankai Gong, Meiling Chen, Quan Li, Shengxing Liu, Shanjun Luo, Huanxiang Dong, Yingke Xu, Huanling Duan, Ling Haung, Chuanzhu Lv
格式:	Article
語言:	英语
出版:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023-05-01
主題:	Sivelestat sodium acute lung injury inflammation oxidative stress JNK/NF-κB Nrf2/HO-1
在線閱讀:	https://www.bjbms.org/ojs/index.php/bjbms/article/view/8549