Acidic/hypoxia dual-alleviated nanoregulators for enhanced treatment of tumor chemo-immunotherapy

Chemotherapy plays a crucial role in triple-negative breast cancer (TNBC) treatment as it not only directly kills cancer cells but also induces immunogenic cell death. However, the chemotherapeutic efficacy was strongly restricted by the acidic and hypoxic tumor environment. Herein, we have successf...

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Bibliographic Details

Published in:	Asian Journal of Pharmaceutical Sciences
Main Authors:	Xiaoju Guo, Xiaoxiao Chen, Jiayi Ding, Feng Zhang, Shunyang Chen, Xin Hu, Shiji Fang, Lin Shen, Chenying Lu, Zhongwei Zhao, Jianfei Tu, Gaofeng Shu, Minjiang Chen, Jiansong Ji
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Subjects:	CaCO3-based nanoparticles Hypoxia attenuation Acidity neutralization Reversal of chemotherapy resistance Enhanced chemo-immunotherapy
Online Access:	http://www.sciencedirect.com/science/article/pii/S1818087624000229