Glycosaminoglycans from <i>Litopenaeus vannamei</i> Inhibit the Alzheimer’s Disease β Secretase, BACE1

Only palliative therapeutic options exist for the treatment of Alzheimer’s Disease; no new successful drug candidates have been developed in over 15 years. The widely used clinical anticoagulant heparin has been reported to exert beneficial effects through multiple pathophysiological pathways involv...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Courtney J. Mycroft-West, Anthony J. Devlin, Lynsay C. Cooper, Scott E. Guimond, Patricia Procter, Marco Guerrini, Gavin J. Miller, David G. Fernig, Edwin A. Yates, Marcelo A. Lima, Mark A. Skidmore
Format:	Article
Language:	English
Published:	MDPI AG 2021-04-01
Subjects:	Alzheimer’s disease amyloid-β BACE1 β-secretase glycosaminoglycan chondroitin sulfate
Online Access:	https://www.mdpi.com/1660-3397/19/4/203