Plasma Small Extracellular Vesicles with Complement Alterations in <i>GRN</i>/<i>C9orf72</i> and Sporadic Frontotemporal Lobar Degeneration

Cutting-edge research suggests endosomal/immune dysregulation in <i>GRN</i>/<i>C9orf72</i>-associated frontotemporal lobar degeneration (FTLD). In this retrospective study, we investigated plasma small extracellular vesicles (sEVs) and complement proteins in 172 subjects (40...

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Bibliographic Details

Published in:	Cells
Main Authors:	Sonia Bellini, Claudia Saraceno, Luisa Benussi, Rosanna Squitti, Sara Cimini, Martina Ricci, Laura Canafoglia, Cinzia Coppola, Gianfranco Puoti, Clarissa Ferrari, Antonio Longobardi, Roland Nicsanu, Marta Lombardi, Giulia D’Arrigo, Claudia Verderio, Giuliano Binetti, Giacomina Rossi, Roberta Ghidoni
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	frontotemporal lobar degeneration <i>GRN</i> <i>C9orf72</i> extracellular vesicles endo-lysosomal pathway plasma
Online Access:	https://www.mdpi.com/2073-4409/11/3/488