Identification of RNA-binding protein hnRNP C targeting the 3’UTR of the TAP-associated glycoprotein tapasin in melanoma

Deregulation or loss of the human leukocyte antigen class I (HLA-I) molecules on tumor cells leading to inhibition of CD8+ T cell recognition is an important tumor immune escape strategy, which could be caused by a posttranscriptional control of molecules in the HLA-I pathway mediated by RNA-binding...

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Bibliographic Details

Published in:	OncoImmunology
Main Authors:	Yuan Wang, Barbara Seliger
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Antigen processing and presentation HNRNPC melanoma RNA-binding protein tapasin tumor immune evasion
Online Access:	https://www.tandfonline.com/doi/10.1080/2162402X.2024.2370928