FusionPathway: Prediction of pathways and therapeutic targets associated with gene fusions in cancer.

Numerous gene fusions have been uncovered across multiple cancer types. Although the ability to target several of these fusions has led to the development of some successful anti-cancer drugs, most of them are not druggable. Understanding the molecular pathways of a fusion is important in determinin...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Chia-Chin Wu, Hannah C Beird, Jianhua Zhang, P Andrew Futreal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Online Access:http://europepmc.org/articles/PMC6075785?pdf=render