'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents.

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	John D Chan, Prince N Agbedanu, Mostafa Zamanian, Sarah M Gruba, Christy L Haynes, Timothy A Day, Jonathan S Marchant
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-02-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003942&type=printable