The double-edged effects of IL-6 in liver regeneration, aging, inflammation, and diseases

Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine and exerts its complex biological functions mainly through three different signal modes, called cis-, trans-, and cluster signaling. When IL-6 binds to its membrane or soluble receptors, the co-receptor gp130 is activated to initiate downstream...

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Bibliographic Details

Published in:	Experimental Hematology & Oncology
Main Authors:	Min-Jun Wang, Hai-Ling Zhang, Fei Chen, Xiao-Jing Guo, Qing-Gui Liu, Jin Hou
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	IL-6 Liver injury Fibrosis, steatosis, carcinogenesis
Online Access:	https://doi.org/10.1186/s40164-024-00527-1