Potential Causal Association between Plasma Metabolites, Immunophenotypes, and Female Reproductive Disorders: A Two-Sample Mendelian Randomization Analysis

Background: While extensive research highlighted the involvement of metabolism and immune cells in female reproductive diseases, causality remains unestablished. Methods: Instrumental variables for 486 circulating metabolites (<i>N</i> = 7824) and 731 immunophenotypes (<i>N</i&g...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Hui-Hui Shen, Yang-Yang Zhang, Xuan-Yu Wang, Cheng-Jie Wang, Ying Wang, Jiang-Feng Ye, Ming-Qing Li
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Subjects:	immunophenotypes metabolites gestational diabetes Mendelian randomization mannose single-nucleotide polymorphisms
Online Access:	https://www.mdpi.com/2218-273X/14/1/116