Systematic optimization and evaluation of culture conditions for the construction of circulating tumor cell clusters using breast cancer cell lines

Abstract Background Circulating tumor cell (CTC) clusters play a critical role in carcinoma metastasis. However, the rarity of CTC clusters and the limitations of capture techniques have retarded the research progress. In vitro CTC clusters model can help to further understand the biological propert...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Jueyao Zou, Qiong Chen, Yong He, Yanhong Pan, Han Zhao, Junfeng Shi, Zhonghong Wei, Suyun Yu, Yang Zhao, Xin Han, Yin Lu, Wenxing Chen
Format:	Article
Language:	English
Published:	BMC 2024-04-01
Subjects:	Circulating tumor cell clusters Tumor metastasis Culture methods Molecular characteristics
Online Access:	https://doi.org/10.1186/s12885-024-12214-9