IL-1β and TNFα Cooperativity in Regulating IL-6 Expression in Adipocytes Depends on CREB Binding and H3K14 Acetylation

IL-6 was found to be overexpressed in the adipose tissue of obese individuals, which may cause insulin resistance. However, the regulation of IL-6 in adipocytes in obesity setting remains to be explored. Since IL-1β and TNFα are increased in obese adipose tissue and promote inflammation, we investig...

詳細記述

書誌詳細

出版年:	Cells
主要な著者:	Areej Al-Roub, Ashraf Al Madhoun, Nadeem Akhter, Reeby Thomas, Lavina Miranda, Texy Jacob, Ebaa Al-Ozairi, Fahd Al-Mulla, Sardar Sindhu, Rasheed Ahmad
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2021-11-01
主題:	interleukin-1β (IL-1β) tumor necrosis factor-alpha (TNFα) adipocytes interleukin-6 (IL-6) H3K14 acetylation
オンライン･アクセス:	https://www.mdpi.com/2073-4409/10/11/3228