Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

Background:Sophora flavescens, a traditional Chinese medicine for treating conditions associated with abnormal skin pigmentation, contains flavonoids with inhibitory effects on tyrosinase. However, their mechanisms of action and their modulatory effects on melanogenesis remain unclear.Methods: Herei...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Fenling Fan, Lanqing Chen, Caihong Chen, Song Ang, Justin Gutkowski, Navindra P. Seeram, Hang Ma, Dongli Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	Sophora flavescens prenylated flavonoid isoanhydroicaritin kurarinone tyrosinase melanogenesis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1422310/full