Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent

Nocturnal polyuria is a prevalent condition associated with significant deterioration in quality of life and increased risk of mortality. Despite its clinical relevance, the underlying pathogenesis is poorly understood, and existing therapies have limited efficacy. A recent study in mouse model reve...

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Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Yosuke Sekii, Hiroshi Kiuchi, Kentaro Takezawa, Norichika Ueda, Takahiro Imanaka, Sohei Kuribayashi, Koichi Okada, Shinichiro Fukuhara, Ryoichi Imamura, Hiromistu Negoro, Yuki Kobayashi, Hikaru Kobayashi, Norio Nonomura
Format:	Article
Language:	English
Published:	Elsevier 2025-03-01
Subjects:	NCC Nocturia Nocturnal polyuria Oxidative stress Silicon Sodium
Online Access:	http://www.sciencedirect.com/science/article/pii/S240558082500010X