Molecular evidence of widespread benzimidazole drug resistance in Ancylostoma caninum from domestic dogs throughout the USA and discovery of a novel β-tubulin benzimidazole resistance mutation.

Ancylostoma caninum is an important zoonotic gastrointestinal nematode of dogs worldwide and a close relative of human hookworms. We recently reported that racing greyhound dogs in the USA are infected with A. caninum that are commonly resistant to multiple anthelmintics. Benzimidazole resistance in...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Abhinaya Venkatesan, Pablo D Jimenez Castro, Arianna Morosetti, Hannah Horvath, Rebecca Chen, Elizabeth Redman, Kayla Dunn, James Bryant Collins, James S Fraser, Erik C Andersen, Ray M Kaplan, John S Gilleard
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-03-01
Online Access:	https://doi.org/10.1371/journal.ppat.1011146