Minnelide combined with anti-ANGPTL3-FLD monoclonal antibody completely protects mice with adriamycin nephropathy by promoting autophagy and inhibiting apoptosis

Abstract Minimal change disease (MCD) is the common type of nephrotic syndrome (NS) in children. Currently, there is an urgent need to explore new treatments because of the significant side effects of long-term use of glucocorticoids and immunosuppressive drugs and the failure to reduce proteinuria...

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Bibliographic Details
Published in:Cell Death and Disease
Main Authors: Baowei Ji, Junchao Liu, Ye Yin, Hong Xu, Qian Shen, Jian Yu
Format: Article
Language:English
Published: Nature Publishing Group 2023-09-01
Online Access:https://doi.org/10.1038/s41419-023-06124-0