Transcription Factor-Mediated Generation of Dopaminergic Neurons from Human iPSCs—A Comparison of Methods

Dopaminergic neurons are the predominant brain cells affected in Parkinson’s disease. With the limited availability of live human brain dopaminergic neurons to study pathological mechanisms of Parkinson’s disease, dopaminergic neurons have been generated from human-skin-cell-derived induced pluripot...

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Bibliographic Details
Published in:Cells
Main Authors: Kirstin O. McDonald, Nikita M. A. Lyons, Luca K. C. Gray, Janet B. Xu, Lucia Schoderboeck, Stephanie M. Hughes, Indranil Basak
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Subjects:
human-induced pluripotent stem cells
dopaminergic neurons
transcription factors
ASCL1
LMX1A
NURR1
Online Access:https://www.mdpi.com/2073-4409/13/12/1016

Internet

https://www.mdpi.com/2073-4409/13/12/1016

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