Hepatocyte-Specific Deletion of HIF2α Prevents NASH-Related Liver Carcinogenesis by Decreasing Cancer Cell ProliferationSummary

Background & Aims: Hypoxia and hypoxia-inducible factors (HIFs) are involved in chronic liver disease progression. We previously showed that hepatocyte HIF-2α activation contributed significantly to nonalcoholic fatty liver disease progression in experimental animals and human patients. In t...

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Bibliographic Details

Published in:	Cellular and Molecular Gastroenterology and Hepatology
Main Authors:	Beatrice Foglia, Salvatore Sutti, Stefania Cannito, Chiara Rosso, Marina Maggiora, Riccardo Autelli, Erica Novo, Claudia Bocca, Gianmarco Villano, Naresh Naik Ramavath, Ramy Younes, Ignazia Tusa, Elisabetta Rovida, Patrizia Pontisso, Elisabetta Bugianesi, Emanuele Albano, Maurizio Parola
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Subjects:	HIF-2α NAFLD NASH Hepatocellular Carcinoma
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352345X21002162