Targeting mitophagy in diabetic retinopathy: novel insights into SQSTM1/BNIP3L pathway regulated by luteolin

ObjectiveDiabetic retinopathy (DR) is a leading microvascular complication of diabetes. Luteolin, a flavonoid with known anti-inflammatory and antioxidant properties, has demonstrated therapeutic potential in early investigations for the treatment of DR. However, its precise molecular mechanisms rem...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Shuyan Zhang, Jiajun Wu, Yinjian Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	diabetic retinopathy monocytes Sqstm1 Bnip3L luteolin
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1593213/full